Bills vs Rams kickoff game: preview, prediction, starting lineups, odds, picks, line, spreads, live stream, tv, injury report

Although the Los Angeles Rams are the favorites to win the 2022 NFL Kickoff Game, the Buffalo Bills are the favorites to win the 2023 Super Bowl. The Bills enter the NFL Kickoff Game in 2022 as the favorite despite the fact that the Rams are the champions and host the NFL Week 1 matchup. That’s because, with a Josh Allen-led offense and one of the NFL’s top defenses, they are also expected to win Super Bowl LVII.

Behind quarterback Matthew Stafford and receiver Cooper Kupp, who just had a great season, the Rams have a potent offense of their own. The Bills famously made it to the Super Bowl four times in a row (1990-93) but lost all four times, while the Rams have won two Super Bowls (1999, 2021). 

Without further ado, take a look at the Bills vs. Rams preview, prediction, starting lineups, odds, picks, line, spreads, live stream, tv, and injury report.

Bills vs Rams Series History

In the previous eight years, Buffalo has defeated Los Angeles in both of their games.

  • Sep 27, 2020 – Buffalo 35 vs. Los Angeles 32
  • Oct 09, 2016 – Buffalo 30 vs. Los Angeles 19

Bills vs Rams picks and predictions

Since the point spread is essentially neutral, spectators should anticipate a close game. We’ll find out if the outcome is as close as the odds via download line bet suggest or if one of these teams is capable of an unexpected rout.


Rams 30, Bills 24

Bills vs Rams odds, line, spreads

Money line

Under Sean McVay, the Rams are 5-0 in Week 1, so it seems inconceivable that they will lose this season’s opener. It is expected that the RAMS (+115) will triumph handily, especially because they are playing at home and the odds are in their favor.

Against the spread

The Rams have been excellent in their season openers under McVay, and they have never lost when the spread has been used. They’ve gone 5-0 ATS in Week 1 over the previous five years, and they’re currently receiving 2.5 points versus the Bills at home.

Even selecting the Rams +2.5 at -105 is a good bet; but, the Rams to win outright at +115 is still the superior value. Take the RAMS +2.5 (-105) to cover the spread, however it’s best to place a smaller wager as insurance for your ML bet.


The Rams starters will be playing in their first game, but it is inconceivable that it will take them long to get rolling. They made a 34 against the Chicago Bears in Stafford’s debut last year. Consequently, when everything is taken into account, the OVER 51.5 (-112).

Bills vs Rams: Time and Location

Here is the time and place for the kickoff game,

  • Time: Thursday at 8:20 p.m. ET
  • Location: SoFi Stadium, Inglewood, California

Bills vs Rams: TV channels

Every week, different games will air on NBC, CBS, Fox, and ESPN, with some games airing on NFL Network as well. Non-nationally televised games will only be available to local market viewers. NFL+, the NFL’s official streaming platform, will broadcast network content for those who want to watch national games on the network. FuboTV, which offers a free trial for nationally aired games, is another option.

How to watch Bills vs Rams live stream?

The Bills vs Rams kickoff match may be streamed on a number of free online sources. However, the majority of those free live streaming services are unstable and require subscriptions or a one-time purchase. You may also have issues with uninvited advertisements.

With that in mind, we’ve assembled a list of websites that provide live NFL game broadcasts. You may therefore watch the Bills vs. Rams game on fuboTV. You can check the following website or platforms to enjoy the Bills vs Rams kickoff game for free as well.


Bills vs Rams: Starting Lineups

As both team’s offenses are capable of scoring points at will, a high scoring game is anticipated. Since switching sides, Von Miller will now compete against the teammates he shared last year’s grand prize with. The star-studded lineups of both teams will put on some incredible performances for the fans during the clash of the titans.

Buffalo Bills:

QB – Josh Allen | RB – Devin Singletary, James Cook | WR – Stefon Diggs, Gabe Davis, Isaiah McKenzie | TE – Dawson Knox, Tommy Sweeney | OL – Dion Dawkins, Roger Saffold, Mitch Morse, Ryan Bates, Greg Van Roten, David Quessenberry.

DL – Gregory Rousseau, Ed Oliver, DaQuan Jones, Von Miller | LB – Tremaine Edmunds, Matt Milano,Terrel Bernard | CB – Dan Jackson, Christian Benford, Kaiir Elam | S – Jordan Poyer, Micah Hyde | P – Sam Martin.

Los Angeles Rams:

QB – Matthew Stafford | RB – Cam Akers, Darrell Henderson Jr. | WR – Cooper Kupp, Allen Robinson | TE – Tyler Higbee, Brycen Hopkins | OL – Joe Noteboom, David Edwards, Brian Allen, Bobby Evans, Rob Havenstein.

DL – A’Shawn Robinson, Greg Gaines, Aaron Donald | LB – Ernest Jones, Bobby Wagner, Leonard Floyd | CB – Jalen Ramsey, Troy Hill | – Taylor Rapp, Nick Scott | P – Riley Dixon.

Bills vs Rams: Injury Report

In order to get off to the greatest possible start, Sean McVay and Sean McDermott will undoubtedly be thrilled to have basically their whole roster accessible. Three players total from both organizations are on the injured list. Besides, it’s a little unexpected that the visiting Bills are the favorites in this game given that the Rams are on the road and the defending Super Bowl champions.

Buffalo Bills

Player Position Type of Injury Injury Status
Tommy Doyle OL foot Questionable
Quintin Morris TE Hamstring Out

Los Angeles Rams

Player Position Type of Injury Injury Status
Van Jefferson WR Knee Out

Zahid Iqbal

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